The maternal nucleolus is essential for early embryonic development in mammals

OGUSHI, S., PALMIERI, CH., FULKOVÁ, H., SAITOU, M., MIYANO, T & FULKA, Jr., J.. The maternal nucleolus is essential for early embryonic development in mammals. Science. 2008, roč. 319, č. February, s. 613-616.
OGUSHI, S., PALMIERI, CH., FULKA, Helena, SAITOU, M., MIYANO, T and FULKA, Josef Jr. The maternal nucleolus is essential for early embryonic development in mammals. Science, 2008, 319, 613-616. ISSN 0036-8075.
Year2008
CathegoryScientific publication in impacted journals
Internal link8002.pdf
Abstract

The article describes the essential role of maternal nucleoli for early embryonic development in mammals. These experiments are based on our originalenucleolation techniques that enables us to manipulate the oocyte nucleoli. We showed, that these nucleoli are not essential for oocyte maturation. Once removed, they are re-assembled again. Moreover, the oocyte nucleolar material cannot be replaced with somatic or embryonic stem cell nucleolar material.