Methodology provides a comprehensive instruction for creation an individual plan biosecurity (biological security) aimed to reduce the probability of transmission diseases both in any one breeding (operation) and or between different farms. There were analysed the precautions to prevent the penetration of infectious agents into farm through persons, animals, technological systems and equipment, transport and the farm sanitation. Biosecurity as an integral part of herd health management is an important requirement for the production of healthy and biologically wholesome raw materials and foodstuffs of animal origin.